Epinephrine (1 mg/mL) - Pediatric (LALS, ALS): Dose is 0.01 mg/kg IM not to exceed 0.3 mg. What is the maximum single IM dose for this concentration?

• A. 0.2 mg
• B. 0.3 mg
• C. 0.5 mg
• D. 1.0 mg

Answer: (B)

Pediatric dosing uses a weight-based calculation with a safety ceiling. The dose is 0.01 mg per kilogram IM, but you should not exceed 0.3 mg per dose. So the largest dose you would administer is the smaller of the weight-based dose or the 0.3 mg cap. Since the concentration is 1 mg/mL, 0.3 mg corresponds to 0.3 mL. Therefore the maximum single IM dose is 0.3 mg (0.3 mL of a 1 mg/mL solution). The other options exceed the allowed maximum or are simply lower than the cap, so they’re not the maximum.