In patients age 9 and older, what is the maximum total dose of Ondansetron that may be given prior to base hospital contact?

• A. 4 mg
• B. 8 mg
• C. 12 mg
• D. 16 mg

Answer: (C)

When dosing ondansetron in older children, you can give multiple small doses rather than a single larger one, but there is a cap on the total amount you may administer before needing base hospital approval. Each dose is up to 4 mg, and you may repeat doses if needed. The protocol for patients aged 9 and older allows a maximum prehospital total of 12 mg. So you could give three 4 mg doses before you must contact the base for further orders. A single 4 mg dose or two 4 mg doses stay within this limit, while 16 mg would exceed it and require base hospital confirmation for additional dosing.