In pediatric seizures when midazolam is not available, what is the IV/IO dose of Diazepam (single dose)?

• A. 0.2 mg/kg IV/IO
• B. 0.15 mg/kg IV/IO
• C. 0.05 mg/kg IV/IO
• D. 0.1 mg/kg IV/IO

Answer: (D)

When a pediatric seizure requires a benzodiazepine and midazolam isn’t available, diazepam given IV/IO is used to stop the convulsions. The dose is chosen to balance rapid seizure control with a safe side-effect profile in children. A single IV/IO dose of diazepam at 0.1 mg/kg delivers effective anticonvulsant action quickly while reducing the risk of respiratory depression and deep sedation that higher doses can cause. Substantially higher doses increase the chance of airway compromise, and noticeably lower doses may not stop the seizure promptly. If the seizure persists, follow your protocol for reassessment and potential additional management, all while monitoring the child closely for breathing and airway safety.