What is ondansetron used for in ICEMA standing orders?

• A. Sedation
• B. Seizure management
• C. Management of nausea and vomiting
• D. Pain relief

Answer: (C)

Ondansetron is an antiemetic. It works by blocking serotonin (5-HT3) receptors in the gut and the brain’s vomiting center, which reduces the nausea and vomiting reflex. In ICEMA standing orders, this makes it the appropriate choice for managing nausea and vomiting. It’s not used for sedation, seizure control, or pain relief, which are addressed by other drug types. Commonly, a standing order might use a 4 mg dose given IV or IM (and sometimes repeated if needed). Be aware of possible side effects like headache or dizziness, and take precautions in patients with a prolonged QT interval or electrolyte disturbances.