What is the standard adult dose of Dextrose for hypoglycemia in this protocol?

• A. Dextrose 50% IV bolus
• B. Dextrose 10%/50 ml IV/IO bolus
• C. Dextrose 25%/100 ml IV/IO bolus
• D. Dextrose 10%/250 ml IV/IO bolus

Answer: (D)

In treating hypoglycemia, the goal is to rapidly deliver about 25 grams of glucose to raise blood sugar promptly. In this protocol, that 25-gram dose is provided by a dextrose 10% solution given as an IV/IO bolus: 250 mL of 10% dextrose contains 25 g of glucose (10 g per 100 mL times 250 mL). Administering it as a bolus ensures the glucose is delivered quickly to correct the hypoglycemia.

Other formulations can also supply 25 g (for example, a smaller volume of a more concentrated solution), but this protocol standardizes on the 10%/250 mL combination to achieve the same dose with a practical bolus volume.