When midazolam is not commercially available, which Diazepam dosing option is valid for adults via IV/IO as a single dose?

• A. 5 mg IV/IO
• B. 10 mg IM
• C. 15 mg IV
• D. 5 mg IM

Answer: (A)

When midazolam isn’t available, diazepam can be used as an IV/IO alternative in adults. The valid single-dose amount for IV/IO administration is 5 mg. This dose provides effective effect without the higher risk of oversedation that comes with larger IV doses, and it aligns with the protocol for substituting midazolam when IV/IO access is used. The other options are not appropriate for a single IV/IO dose: they either use the IM route (which isn’t the route in this scenario) or propose a higher IV dose than typically given as a single administration.